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Extraction Summary

1
People
6
Organizations
2
Locations
2
Events
1
Relationships
3
Quotes

Document Information

Type: Investment research report / financial analysis
File Size: 2.17 MB
Summary

This document is page 91 of a Cowen Collaborative Insights investment report dated February 25, 2019. It details the clinical trial results and investor analysis for the drug Epidiolex, specifically focusing on its efficacy in treating seizures (Dravet and LGS) with and without the concomitant use of clobazam, and noting that the drug is effective on its own. While part of a document production marked 'HOUSE_OVERSIGHT', the content is strictly pharmaceutical financial analysis and does not mention Jeffrey Epstein directly.

People (1)

Name Role Context
Michael Cella Recipient/Employee
Email address michael.cella@cowen.com listed in the watermark as the intended recipient.

Organizations (6)

Name Type Context
Cowen
Author of the report (Cowen Collaborative Insights).
GW
Mentioned as the company noting results ('GW noted...') and presenting analysis; likely GW Pharmaceuticals.
NEJM
New England Journal of Medicine, where trial results were published.
Massachusetts General Hospital
Provided abstracts from compassionate use experience.
University of Alabama Birmingham
Provided abstracts from compassionate use experience.
House Oversight Committee
Bates stamp indicates 'HOUSE_OVERSIGHT'.

Timeline (2 events)

2017
AES 2017 (American Epilepsy Society meeting) where GW presented pooled analysis.
N/A
GW
May 2018
Publication of trial results in NEJM.
N/A

Locations (2)

Location Context
Source of compassionate use data.
Source of compassionate use data.

Relationships (1)

Michael Cella Employment/Affiliation Cowen
Email address michael.cella@cowen.com in watermark.

Key Quotes (3)

"Epidiolex appeared to be well tolerated in the trial."
Source
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Quote #1
"The analyses from these two institutions also concluded that Epidiolex does not need to be combined with clobazam to be effective."
Source
HOUSE_OVERSIGHT_024907.jpg
Quote #2
"We believe that investors had been hoping for a 12-15% placebo-adjusted 50% response rate for patients on Epidiolex without clobazam in order to be satisfied that Epidiolex was active without clobazam, and therefore the results cleared this bar."
Source
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Quote #3

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