HOUSE_OVERSIGHT_013580.jpg

2.03 MB

Extraction Summary

3
People
2
Organizations
1
Locations
2
Events
2
Relationships
2
Quotes

Document Information

Type: Scientific manuscript / book excerpt (house oversight production)
File Size: 2.03 MB
Summary

This page (80) from a House Oversight production (Bates 013580) appears to be a scientific text discussing nonlinear dynamical systems and entropy in the context of behavioral psychology. It details experiments by Paulus and Geyer regarding rat behavior under stimulant drugs and defines 'topological entropy' and 'metric entropy.' The text also introduces Karen Selz from Emory University regarding her work on human subjects.

People (3)

Name Role Context
Paulus Researcher
Cited for work showing effects of stimulant drugs on rats (likely Martin P. Paulus)
Geyer Researcher
Cited for work showing effects of stimulant drugs on rats (likely Mark A. Geyer)
Karen Selz Research Professor of Psychiatry
Mentioned as a professor at Emory University who devised experiments on human subjects

Organizations (2)

Name Type Context
Emory University
Employer of Karen Selz
House Oversight Committee
Implied by Bates stamp 'HOUSE_OVERSIGHT'

Timeline (2 events)

Unknown (Past)
Rat experiments involving stimulant drugs and spatial movement analysis
Laboratory setting (implied)
Unknown (Past)
Human experiments using unobtrusive measures
Emory University

Locations (1)

Location Context
Location of Emory University

Relationships (2)

Paulus Research Partners Geyer
the work of Paulus and Geyer showed...
Karen Selz Employment Emory University
Karen Selz, a Research Professor of Psychiatry at Emory University

Key Quotes (2)

"In man, low doses of amphetamine tend to increase the rate and creativity of thought streams and high doses generate fixed ideas and paranoid delusions."
Source
HOUSE_OVERSIGHT_013580.jpg
Quote #1
"time-dependent generation of new possibilities is called topological entropy, HT and the entropy associated with the distribution of probabilities is called the metric entropy, HM."
Source
HOUSE_OVERSIGHT_013580.jpg
Quote #2

Full Extracted Text

Complete text extracted from the document (2,396 characters)

or left. The new information being generated by the pattern of spatial orbits took the form of sequences of numbers or symbols representing the sequence of labeled boxes. The complexity of these numeric or symbol sequences was then quantified in a variety of ways including the use of two fundamental measures of dynamical entropy.
One measure reflects how many new, previously unexplored boxes were entered by the rat per unit of time. This rate represents a percent of the possible. The second measure reflects how much of the time did the rat in each box visited as a distribution of the probable. The rate of expansion of the possible and the relative time in occupancy of these possibles, the probables, form the bases for the computation of these two kinds of entropies. For example, the work of Paulus and Geyer showed that the administration of a very small amount of stimulant drug, compared with a salt water control, led to an increase in the first measure of the number of new, previously unexplored, boxes entered per unit time. With respect to the second measure, the stimulant drug augmented exploratory activity was also more uniformly distributed over the possible boxes, making for more uniform probability. Administration of higher doses of stimulant drugs, at a critical dose, led suddenly to more spatially and temporally restricted and stereotyped patterns of motion of the rats, compulsive circling alternating with frozen sniffing. Both contributed to a decrease in the possible and nonuniformity in the distribution of the probabilities. In man, low doses of amphetamine tend to increase the rate and creativity of thought streams and high doses generate fixed ideas and paranoid delusions. In the statistical approach to nonlinear dynamical systems, time-dependent generation of new possibilities is called topological entropy, HT and the entropy associated with the distribution of probabilities is called the metric entropy, HM. These kinds of entropies have also been used to quantitate characteristic patterns of in human behavior as well.
We have previously mentioned these measures as used in human experiments by Karen Selz, a Research Professor of Psychiatry at Emory University in Atlanta. Recall that she devised a set of experiments leading to unobtrusive measures made on human subjects by asking them to remove, as many as they
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