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Document Information
Type:
Educational curriculum / lesson plan / investigative production
File Size:
1.78 MB
Summary
This document is a page from an educational curriculum titled 'Genetics & Human Health' produced by 'Nautilus Education | Beta Product.' It contains a lesson plan and vocabulary definitions related to DNA, muscular dystrophy, and cancer. The document bears the Bates stamp 'HOUSE_OVERSIGHT_015488,' indicating it was produced as part of a US House Oversight Committee investigation, likely related to Jeffrey Epstein's financial ties to scientific organizations or publications (Epstein was a known investor in Nautilus magazine).
Organizations (2)
| Name | Type | Context |
|---|---|---|
| Nautilus Education | ||
| House Oversight Committee |
Key Quotes (3)
"Since DNA is often heralded as the “code of life,” what clues can mutations—changes to the DNA sequence—tell us about human health and disease?"Source
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Quote #1
"Orphan diseases: diseases that have yet to be “adopted” by the pharmaceutical industry because there are very few incentives to develop new medications to treat or prevent them."Source
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Quote #2
"An Unlikely Cure Signals Hope for Cancer explores how specific mutations in a patient’s cancer can be used to a patient’s advantage."Source
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Full Extracted Text
Complete text extracted from the document (2,617 characters)
NAUTILUS EDUCATION | BETA PRODUCT
Genetics & Human Health
Since DNA is often heralded as the “code of life,” what clues can mutations—changes to the DNA sequence—tell us about human health and disease? The pair of articles in the Genetics and Human Health module will explore the consequences of mutations in the context of cancer treatment and rare diseases such as muscular dystrophy. Their Giant Steps to a Cure discusses the challenges associated with treating a rare form of muscular dystrophy. An Unlikely Cure Signals Hope for Cancer explores how specific mutations in a patient’s cancer can be used to a patient’s advantage.
Lesson Plan
Ask students to read both of the articles for homework. Briefly introduce or review the vocabulary words in class. Assign the questions listed under “Reading Comprehension” for them to complete along with the reading and ask them to come up with one question for further discussion.
Start class by asking students if they have any questions about the readings. Ask them to contribute their discussion questions (in addition to the ones provided under Deep Thinking / Discussion questions). Have the class brainstorm and answer both discussion questions. 15 MIN.
Next, break the class up into four groups for the Suggested Activity. Assign each group to one protein that is listed in the interactive. 15 MIN.
Have each group present their thoughts to the class for further discussion. 15 MIN.
Teacher’s Notes: Their Giant Steps to a Cure, and An Unlikely Cure Signals Hope for Cancer
VOCAB WORDS
Muscular dystrophy: a genetic disease marked by progressive weakening of the muscles. Some forms of muscular dystrophy are seen in infancy or childhood.
Orphan diseases: diseases that have yet to be “adopted” by the pharmaceutical industry because there are very few incentives to develop new medications to treat or prevent them. Orphan diseases can be rare or they are common diseases that have been ignored (e.g.: tuberculosis, cholera, typhoid, malaria).
Calpainopathy: a rare type of muscular dystrophy characterized by symmetric and progressive weakness of proximal (limb-girdle) muscles.
Cancer: A term used to describe disease in which abnormal cells divide without control and are able to invade into other tissues. Cancers are often categorized based on the organ or cell type they originate in.
Oncologist: A doctor who specializes in treating patients with cancer.
Outlier: An observation that deviates from a majority and can be seen to be a rare event. In the context of this piece, the outliers are patients who respond
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