HOUSE_OVERSIGHT_015499.jpg
2.19 MB
Extraction Summary
7
People
6
Organizations
2
Locations
2
Events
2
Relationships
4
Quotes
Document Information
Type:
Published article / magazine feature (likely from nautilus)
File Size:
2.19 MB
Summary
This document is a page from a publication (likely Nautilus) discussing advances in cancer research, specifically genetic sequencing and 'outlier' cases. It highlights the work of researchers at MD Anderson and Washington University who use genomic analysis to repurpose drugs for specific genetic mutations (such as FLT3, RAD50, and TSC1). The document bears a 'HOUSE_OVERSIGHT' Bates stamp, indicating it was part of a document production to the House Oversight Committee, likely related to inquiries involving Jeffrey Epstein due to his known interest in and funding of scientific research.
People (7)
| Name | Role | Context |
|---|---|---|
| Funda Meric-Bernstam | Chair of the Department of Investigational Cancer Therapeutics |
Based at MD Anderson; leads the unusual responders program.
|
| Conley | Researcher |
Mentioned alongside Doroshow regarding pinpointing patients for abandoned drugs.
|
| Doroshow | Researcher |
Mentioned alongside Conley regarding pinpointing patients for abandoned drugs.
|
| Elaine Mardis | Co-director / Professor of Genetics |
Genome Institute at Washington University; coined the term 'Maserati approach'.
|
| Lukas Wartman | Doctor / Patient |
Young Washington University doctor with leukemia who went into remission after genetic analysis.
|
| Solit | Researcher |
Leads a group solving 'exceptional responder' mysteries; working on tests for TSC1 mutations.
|
| Kat McGowan | Author |
Contributing editor at Discover magazine and independent journalist.
|
Organizations (6)
Timeline (2 events)
Unknown (Past)
Lukas Wartman's leukemia went into remission after genetic analysis revealed FLT3 gene expression.
Washington University
Locations (2)
| Location | Context |
|---|---|
Relationships (2)
Professor of genetics and Genome Institute co-director
Chair of the Department of Investigational Cancer Therapeutics at MD Anderson
Key Quotes (4)
"We’re talking about small subsets of patients that together make a radical change"Source
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Quote #1
"The Maserati approach"Source
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Quote #2
"To look at these individuals’ cancers can tell us a lot more than just a random case of cancer"Source
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Quote #3
"There’s a phenotype—a response—that gives you information about the genes."Source
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Quote #4
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